

Salesforce customers/users have issues adding email to the activity tab and customizing the email to send new mail every time.
Auto-response rules let you automatically send email responses to lead or case submissions based on the record’s attributes. For example, you can send an automatic reply to customers to let them know someone at your company received their inquiry.
To create a response rule for cases, from Setup, enter Auto-Response Rules in the Quick Find box, then select Case Auto-Response Rules. On the Auto-Response Rules page:
Enable Email-to-Case and then create a custom email action
Enable Email-to-Case and then create a custom email action.
To enable email under activity in the case, first, enable Email-to-Case·
Select “Send email” as the action type and fill the label, Name.
To prevent auto-reply, Set blank values as the Predefined Field Values for HTML body and subject respectively.

Every email is treated as a new email and not a reply or a forward.
None.
This is the only way to avoid auto-reply in email for case objects in Salesforce.